also see Cancer in dogs
also see Hemangiosarcoma, Hemangiopericytomas
and Hemangiomas
also see Cough
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Lung cancer
Question: Dear Dr. Mike,
My twelve year old shepherd mix female, BeniHana, was diagnosed last
week
with a malignant tumor on her left lung about 4" by 5". It was
aspirated
to confirm its malignancy but we do not know what type of cancer it
is. My feeling is that it wouldn't be sensible to attempt to
treat it
with surgery, chemo, and/or radiation. My vet didn't want to
sway me one
way or the other, however, and I wondered what you thought. Surgery
sounds highly invasive and painful and likely not very practical.
My vet did say we could give her prednisilone (reduce inflammation)
and
lasix (fluid reduction), however, as a palliative approach.
My questions are these:
1. What range of time has she got left (without any interventive treatment)?
2. She only coughs occasionally (it started about six weeks ago)--what
other symptoms should I look for to determine how she is faring?
3. Last night, as she slept I noticed fast breathing and her
heart, which
has been shoved over by the tumor, was visibly beating against her
chest
cavity. I measured its rate to be about 126/minute. Is
this anywhere
normal for a 48 lb. dog? If not, what causes the very rapid rate?
4. I am very concerned about her comfort level, and I want to
do the
right thing. This is very hard emotionally for me, and probably
physically for her. She still eats well and drinks large quantities
of
water. When is the time right to consider euthanasia? I
really don't
want her to to have endure much suffering. She already has endured
years
of painful hip dysplasia.
5. How common is lung cancer in dogs? Without knowing what type
of cancer
it is, can I know whether it can readily metastisize?
Thank you so much.
Wendy
Answer: Wendy-
I am sorry, but it isn't possible to tell you much about the expected
behavior of a tumor without knowing what type of tumor it is.
Sometimes
the only way to really identify a tumor is to remove it, or to at least
obtain a piece of it surgically, so that a pathologist can examine
the
architecture of the tumor for clues as to what it is. This happens
most
frequently when cell types have lost most of their identifying features,
making a needle biopsy sample inconclusive. That is a bad sign, usually
indicating a higher tendency towards malignancy and rapid growth, but
beyond that it is isn't possible to say much.
Coughing can be evaluated by frequency, harshness and productivity (what
comes up during the coughing episode). Very frequent coughing, deep
harsh
coughing and the production of excessive amounts of phlegm, or other
substances such as blood, are signs that a lung problem is worsening.
Tiring readily, weight loss and unexplained fever occur with malignant
tumors when they begin to really use a lot of the body's energy. Anemia
is
a frequent problem when malignant tumors are present and monitoring
for it
can be helpful in determining if the tumor is causing more problems
than
are visible. This is particularly true of tumors such as hemangiosarcoma,
which can cause internal bleeding.
126 beats per minute could be within the normal range for a sleeping
dog of
her size, depending on what part of the sleep cycle she is in. Dogs
have
REM (rapid eye movement) sleep, which is when dreaming occurs in people,
and heart rates can get high during this phase of sleep. The normal
heart
rate for dogs that are awake ranges from 70 to 180 bpm, with small
dogs
having higher heart rates and larger dogs slower rates, so this heart
rate
is not out of the normal expected range when awake. I couldn't find
specific expected heart rate ranges for sleeping dogs.
I think it is a really good idea to consider pain relief medications,
even
if you are not currently seeing signs of pain. Carprofen (Rimadyl Rx)
and
etodolac (Etogesic Rx) are good initial choices. If there are signs
of
visible pain it may be better to use narcotic pain relievers such as
morphine or fentanyl (available as Duragesic Patches Rx). It
is reasonable
to presume that some pain is present when there are malignant tumors
and
these would help with the arthritis, anyway.
Most dogs that are reaching the point where they are no longer able
to
enjoy life much stop eating, or have drastic reductions in appetite.
They
may refuse to play or to interact with their friends. In extreme cases,
they may be totally inattentive to urinary habits or bowel movements,
losing all pretense of normal household behaviors or not even
moving away
from a urine puddle or bowel movement. Almost all pet owners have enough
empathy with their pets to recognize the time when their pet has given
up
fighting an illness. There is just a time when you stop wondering if
the
time is right to consider euthanasia and you just know that the time
has
arrived.
Primary lung cancer (cancer coming from lung tissue) is rare in dogs,
so
the odds are very high that a tumor seen in the lungs is a metastasis
from
a tumor somewhere else. This is not always the case but it is a reasonable
presumption. So in most cases, just seeing a tumor in the lungs is
reason
to suspect metastatic cancer.
It may be worth asking your vet for a referral to a veterinary oncologist
(cancer specialist) or internal medicine specialist, just to hear what
the
options are for identifying the tumor and treatment. You may decide
that it
isn't something you wish to pursue but you would have a better idea
of what
the potential for treatment and the prognosis would be. Sometimes knowing
those things is worth making a trip to a specialist. On the other
hand, if
you are certain that you do not wish to pursue surgery, chemotherapy
or
radiation therapy then knowing the exact type of tumor and the prognosis
is
not quite as important. In that case, just treating the symptoms as
they
come along and providing good nursing care until BeniHana lets you
know she
is too uncomfortable to be happy may be the best option. Your vet can
help
with the palliative measures you mentioned and with pain control.
Trying to keep things interesting and giving in the temptation to spoil
BeniHana some with special foods or activities can make her life much
more
enjoyable, despite the physical problems that might develop due to
the tumor.
Mike Richards, DVM
11/4/2000